PhD Student GROW-School for Oncology and Developmental Biology - Department of Toxicogenomics

Solliciteer binnen 13 dagen op deze vacature

In this project the main objective is to obtain more insight in the biological processes underlying the exposure of a cell model to a (toxic) substance. These biological processes are often dynamic, and thus their activity should be monitored at multiple time points. Therefore, this dynamic activity will be captured by monitoring gene expression, miRNA and epigenetic changes at multiple time points using RNA-seq and MeDIP-seq. In addition, multiple phenotypic endpoints are being measured as well in these time-series experiments.

Different statistical and mathematical models as well as visualization tools will be applied to achieve the objective. Developing or improving/adjusting methods for data integration, capturing time dependencies/time delays and causality will be part of this project.

We seek a PhD student who has experience in computer programming and algorithm development (MATLAB, R, Python, Java, Scala, C++ or equivalent) with a focus on computational biology applications. Preference will be given to candidates with a strong affinity for developing solutions for solving computational and biological problems.

Temporary employment for 4 years.

Your salary would be € 2.191 gross per month in the first year up to € 2.801 gross per month in the fourth year, according to the PhD-student salary scale.

Each year an evaluation will take place.

The terms of employment of Maastricht University are set out in the Collective Labour Agreement of Dutch Universities (CAO). Furthermore, local UM provisions also apply. For more information look at the website http://www.maastrichtuniversity.nl > Support > UM employees.

Employment

Temporary, 4 years

Organisation

http://www.maastrichtuniversity.nl/

Maastricht University is renowned for its unique, innovative, problem-based learning system, which is characterized by a small-scale and student-oriented approach. Research at UM is characterized by a multidisciplinary and thematic approach, and is concentrated in research institutes and schools. Maastricht University has around 16,000 students and 4,000 employees. Reflecting the university's strong international profile, a fair number of both students and staff are from abroad. The university hosts 6 faculties: Faculty of Health, Medicine and Life Sciences, Faculty of Law, School of Business and Economics, Faculty of Humanities and Sciences, Faculty of Arts and Social Sciences, Faculty of Psychology and Neuroscience.