There’s a simple purpose that sits at the heart of our business: to enable people with life-altering conditions to lead better lives. We want to be the company that imagines and leads the future of healthcare for people with life-altering conditions, creating value for society.

Founded in 1986, Shire is a fast-growing company with more than 5,000 employees all fully focused on a single purpose: to enable people with life-altering conditions to lead better lives. Our Brave culture encourages a challenge to the status quo, collaboration across cultures and geographic boundaries, the pursuit of innovation, and a firm focus on responsibility across everything we do. 

Shire’s operations are structured across three businesses – Human Genetic Therapies, Regenerative Medicine, and Specialty Pharmaceuticals – with a major U.S. presence in Massachusetts, California and Pennsylvania respectively.  

With international hub offices in the United Kingdom, Switzerland and Brazil, our Shire team is structured for strategic geographic expansion based on business milestones and opportunities.