Senior Scientist Protein Characterisation   

AF/016252

South                                                                          

c28-32k

As senior scientist in protein characterisation you will provide protein characterisation and method validation services in support of process and product development of proteins which are manufactured for a diverse and expanding worldwide client base.  As well as significant protein characterisation experience considerable mass spectrometry experience is essential for this role.

RESPONSIBILITIES:

• Carry out characterisation of recombinant protein products by mass spectrometry, electrophoresis and HPLC to support process and product development as required to meet project timelines and budget.

• Preparation of assay write ups, protocols and reports (cGMP and non-GMP) to document product characterisation, comparability and assay validation activities for process development and regulatory submissions as appropriate.


• Maintenance of documentation and equipment required to support product characterisation.

 

QUALIFICATIONS AND EXPERIENCE

 

  • Degree / MSc/ PhD Biology/ Life Science Biotechnology Chemistry Biochemistry
  • Significant experience in the characterisation of proteins and their post translational modifications by mass spectrometric methods, chromatographic, electrophoretic, gained in either an academic or commercial environment.
  • Understanding of the methods and underlying principles of protein characterisation (experience of assays such as SDS-PAGE, IEF, GP/RP/IEX HPLC, peptide mapping, glycosylation analysis, mass spectrometry and Western blot).
  • Good working knowledge of protein chemistry and structure and other biochemical methods applied to protein analysis for cGMP testing of biopharmaceuticals.
  • The successful applicant will need to demonstrate a supportive, flexible and proactive attitude towards their work. Excellent communication skills will be essential.
  • Experience of working to GMP
  • Experience of working for a contract research or manufacturing organisation desirable.


To Apply
Please contact Alison Fisher at Hudson Shribman Scientific Recruitment, quoting reference AF /016252

Due to a high volume of applicant’s only shortlisted candidates will be contacted. If you are not contacted within seven days of submitting your CV please assume that your application will not be taken further.