PhD Studentship: Four-year integrated PhD in Translational Immunology

PhD Studentship: Four-year integrated PhD in Translational Immunology

Cancer Sciences

Location:  Southampton General Hospital
Closing Date:   Friday 22 July 2016
Reference:  749316CM

Lead Institute / Faculty:   Faculty of Medicine, University of Southampton

Main Supervisor: GRAHAM PACKHAM

Other members of the supervisory team: HYWEL MORGAN, FRANCESCO FORCONI, EDD JAMES, TIM ELLIOTT

Duration of the award: 4 YEARS

Project description:

We have an opportunity for a PhD student to join the Doctoral Training Partnership in Translational Immunology with a project offered in the area of development of microfluidic devices for analysis of single-cell signalling responses in human malignant B cells.

Programme Structure

Year 1

In year 1 you will choose three laboratory rotation projects, which will give you the opportunity to work with our research groups who are at the cutting edge of translational immunology.  Laboratory rotations are supplemented with taught modules in Statistical Methods and Quantitative Cell Biology, which includes a hands-on introduction to bioinformatics techniques and computational modelling, using large clinically-relevant datasets.  These will provide training required for the completion of the detailed research project in years 2-4.

You will receive an intermediate award of MRes after successful completion of the first year.  Please note the MRes is not offered for application separately.

Years 2-4

Years 2-4 comprises the MAIN research project “microfluidic devices for time-resolved quantification of single-cell signalling responses in human leukaemia and lymphoma”.

The main goals are to develop novel microfluidic devices which are capable of quantifying signalling responses in thousands of individual malignant B cells obtained from patients with lymphoma or leukaemia . Signalling analysis will be used to probe the biological features of B-cell cancers, and potentially to predict patient outcome. This project will provide training in biomedical engineering, imaging, cancer cells signalling and bioinformatics. The aim is for you to become an active and valued member of the research laboratory led by Professor Packham.

Please contact:  Professor Graham Packham gpackham@soton.ac.uk

Person Specification:

The successful candidate is likely to have the following qualifications:

• A 1^stor 2:1 degree in a relevant discipline and/or second degree with a related Masters

Funding information:

The studentships will be paid at a minimum rate of the standard UK Research Council recommended maintenance stipend (£14,057 in 2015/2016) plus UK fees. Students may also be accepted on a self-funding basis.

Administrative contact and how to apply:

Please complete the University's online application form, which you can find at

https://studentrecords.soton.ac.uk/BNNRPROD/bzsksrch.P_Login?pos=4394&majr=4395&term=201617#_ga=1.34642081.1675618236.1430384755

You should enter Professor Graham Packham as your proposed supervisor. To support your application provide an academic CV (including contact details of two referees), official academic transcripts and a personal statement (outlining your suitability for the studentship, what you hope to achieve from the PhD and your research experience to date).

Informal enquiries relating to the project or candidate suitability should be directed to Professor Graham Packham (email address gpackham@soton.ac.uk).

Closing date:     22nd July 2016 

Interview date:  8^th August 2016

Further details:

• Job Description and Person Specification