Postdoctoral researcher or PhD student in High-Throughput 3D imaging

The Merln Institute for Technology-inspired Regenerative Medicine, where we develop novel and challenging technologies to advance the field of organ regeneration, is looking for a Postdoc or PhD for a collaborative project between the labs for cBITE and CTR.

Job Specifications - (uitleg)

Solliciteer binnen 16 dagen op deze vacature

Job Description

We are currently looking for a Postdoctoral researcher or a PhD candidate for a collaborative project between the laboratories for Cell Biology-Inspired Tissue Engineering (cBITE) and the department of Complex Tissue Regeneration (CTR). cBITE focuses on understanding and applying cell biology principles in biomedical engineering. CTR develops advanced, high-throughput screening technologies to orchestrate the in vitro development of organs (“organoids”). 

Organs function via the coordinated action of spatially ordered, cell types. At Merln, we study development in vitro using organoids and in vivo by implanting bio-active materials. We develop high throughput platforms, automated image analysis and advanced data mining to extract information rich data from 3D tissues.

 This project will focus on implementing advanced high-throughput screening 3D imaging tools to quantify positional information, gene (single-molecule FISH) and protein (fluorescent fusion protein) expression. Novel computational methods will be developed in collaboration with the Imaging Platform at the Broad Institute (Harvard/MIT, Boston). The platforms will be used to study in vitro embryonic development and in vivo cell-biomaterial interaction.

Requirements

Merln invites applications for a full-time postdoctoral researcher or PhD candidate. The candidate will develop knowledge at the exciting crossroads of imaging, bioinformatics and cell biology. The candidate must have a degree in biology, engineering, bioinformatics (or closely related), knowledge in bioinformatics and a strong interest for high-throughput image analysis. Outstanding knowledge of scientific English both in speaking and in reading is required.

Conditions

The full-time postdoctoral position is offered for three years (1+2), with a yearly evaluation. The salary will be set in scale 10 of the Collective Labor Agreement of the Dutch Universities (€ 2.532,00 to €3.997,00 gross per month).

The full-time PhD position is offered for four years (1+3), with a yearly evaluation. The salary will be set in PhD salary scale of the Collective Labor Agreement of the Dutch Universities (€2.174,00 gross per month in first year to €2.779,00 last year).

On top of this, there is an 8% holiday and an 8.3% year-end allowance. The terms of employment of Maastricht University are set out in the Collective Labor Agreement of Dutch Universities (CAO). Furthermore, local UM provisions also apply. For more information look at the website www.maastrichtuniversity.nl > Support > UM employees

Employment: Temporary, 3 years (postdoc)/ 4 years (PhD)

Organisation

http://www.maastrichtuniversity.nl/

Maastricht University is renowned for its unique, innovative, problem-based learning system, which is characterized by a small-scale and student-oriented approach. Research at UM is characterized by a multidisciplinary and thematic approach, and is concentrated in research institutes and schools. Maastricht University has around 16,000 students and 4,000 employees. Reflecting the university's strong international profile, a fair amount of both students and staff are from abroad. The university hosts 6 faculties: Faculty of Health, Medicine and Life Sciences, Faculty of Law, School of Business and Economics, Faculty of Humanities and Sciences, Faculty of Arts and Social Sciences, Faculty of Psychology and Neuroscience.

Department

Merln Institute for Technology Inspired Regenerative Medicine

The Institute for Technology-Inspired Regenerative Medicine (MERLN) strives for a leading position in the field of biomedical engineering by combining creative research with training an interdisciplinary generation of scientists. MERLN’s activities operate at the interface of biology and engineering and aim to maximise outreach at the level of public involvement, development, and the commercialisation of research. MERLN’s vision is based on sharing knowledge, infrastructure, and ambition. Research at MERLN is focused on developing novel and challenging technologies to advance the field of tissue and organ repair and regeneration. The strategy focuses on - but isn't limited to - the development of “smart” biomaterials which can trigger intrinsic tissue repair mechanisms mediated by the patient’s own cells. The primary focus of the research activities is on connective tissue repair and regeneration.

Additional Information

For more detailed information, you can contact the chair of cBITE, Prof. dr. J. de Boer: jan.deboer@maastrichtuniversity.nl and the principal investigator of CTR, dr. N. Rivron n.rivron@hubrecht.eu.