Research Fellow

Job Purpose

To contribute to our understanding of the role of Epstein Barr virus in the pathogenesis of EBV-associated gastric carcinoma. The project is funded by the University of Birmingham and focuses on how Epstein Barr drives the development of gastric carcinoma using novel 3D models of gastric mucosa. These cutting-edge models of gastric mucosa provide the most physiological culture system available and will for the first time enable a systematic analysis of the cell types infected by EBV and how infection modifies these cells both at the epigenetic and genetic level.

Person Specification

• First degree in biology – with a significant cell biology and/or virology component.
• PhD in epithelial cell biology.
• Proven track record in single cell imaging techniques.
• Practical experience in culture of primary epithelial cells.
• Practical experience in molecular biology techniques.
• Practical experience in design and implementation of confocal techniques.
• Practical experience with gene expression analysis, real-time PCR and primer design.
• Experience of epigenetic techniques would be advantageous.
• High level analytical capability
• Effective interpersonal and communication skills (including written and presentational)
• Effective organisational skills and the ability to prioritise work to meet deadlines.
• Evidence of an ability to work individually or as part of a team.
• Fluency in relevant models, techniques or methods and ability to contribute to developing new ones
• Ability to assess resource requirements and use resources effectively
• Understanding of and ability to contribute to broader management/administration processes
• Working knowledge of health and safety requirements within the laboratory setting.