Senior Post-doc FHML; dept Pathology FHML/School for Cardiovascular Diseases/CARIM
Senior Post doc Dept of Pathology, MUMC+ on Mass Spectrometry Imaging and kidney disease Full time Senior Post doc position for 1 year at the Dept Pathology embedded in a collaborative program with the Depts. of Surgery and the Maastricht Multimodal Molecular Imaging Institute M4i at the Maastricht
Job Specifications - (uitleg)
A position for a Senior Post doc, financed by Nierstichting Nederland (the Dutch Kidney Foundation), is available in the Pathology Dept. of Maastricht University Medical Center+, on a collaborative project with the departments of Surgery (Prof. Dr. E. van Heurn and Prof. S. Olde Damink) and M4i (Prof. Dr. Ron Heeren). The group is embedded in the Cardiovascular Research Institute Maatricht (CARIM), as well as NUTRIM School for Nutrition, Toxicology and Metabolism of the Maastricht University Medical Center+.
There is an urgent need to develop biomarkers for early detection of acute and chronic kidney disease in patients, as these diseases are associated wtih higher cardiovascular morbidity and mortality. Previously we found an important role for damage to the microvasculature in an early stage of renal disease development (Steegh et al. JASN 2011). Mass Spectrometry Imaging (MSI) can be used to identify metabolites and hitherto unidentified compounds at a high spatial resolution in tissue sections. In this research project this novel and innovative technique will be applied on renal tissue in early disease stages. In addition it may be possible to participate in studies to unravel the pathofysiological significance of capillary loss for chronic organ dysfunction using animal models and in vitro systems.
This Senior Postdoc project is an excellent opportunity to prepare for a career in applying novel tissue analystical techniques to unravel pathofysiological pathways and ultimately implement them in daily clinical practice.
Applicants should hold a PhD degree in Medicine, Health Sciences or Biology and have experience in a post-doctoral position. Individuals with prior experience in tissue techniques (histology, immunohistochemistry, imaging) and endothelial cell biology (in vivo and in vitro) are encouraged to apply. You should display great team spirit, perseverance, a driven, independent and curious nature, and excellent verbal and written communication skills in English.
The terms of employment of Maastricht University are set out in the Collective Labour Agreement of Dutch Universities (CAO). Furthermore, local UM provisions also apply. For more information look at the website www.maastrichtuniversity.nl > Support > UM employees.
Temporary, 1 year
Maastricht University is renowned for its unique, innovative, problem-based learning system, which is characterized by a small-scale and student-oriented approach. Research at UM is characterized by a multidisciplinary and thematic approach, and is concentrated in research institutes and schools. Maastricht University has around 16,000 students and 4,000 employees. Reflecting the university's strong international profile, a fair amount of both students and staff are from abroad. The university hosts 6 faculties: Faculty of Health, Medicine and Life Sciences, Faculty of Law, School of Business and Economics, Faculty of Humanities and Sciences, Faculty of Arts and Social Sciences, Faculty of Psychology and Neuroscience.
The Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, is one of the top institutes for translational cardiovascular research in Europe. It is among the world leaders in the fields of research into vascular and thrombotic disorders and atrial fibrillation as well as translational heart failure research. It has also made important international contributions to molecular imaging in the cardiovascular field.
With an annual budget of approximately 22,000,000 Euros in 2015, CARIM is one of the largest cardiovascular research institutes in Europe, producing more than 550 scientific articles and approximately 30 PhD dissertations per year. CARIM employs 250 researchers from 13 disciplines, about 120 PhD students and 50 technical and support staff members.
Over the last ten years, CARIM papers have been published in high-impact journals such as the New England Journal of Medicine, JAMA, Nature Medicine, Nature Cell Biology, Cell Metabolism, Journal of Experimental Medicine, Circulation, Lancet Neurology, and the Journal of the American College of Cardiology. Bibliometric analyses illustrate that CARIM publications have been cited 1.97 times more often than the world average for the cardiovascular field in the period of 2009 until 2012.
CARIM is recognized by the KNAW as a research school and as an international training site for Early Stage Researchers in the framework of the Marie Curie Program.
Cardiovascular scientists from around the world join CARIM because it values open communication, close cooperation, high ambitions, good facilities and a critical learning environment.
For additional information you may contact Dr. C.J. Peutz-Kootstra (email@example.com) or Prof. Dr. E. Biessen (firstname.lastname@example.org); +31 4376620.
Applicants should send their curriculum vitae, a motivated application letter including contact information of two references to email@example.com.