Scientist, Cell Culture & Automation - Molecular Discovery Job
- Employer
- Merck
- Location
- West Point PA
- Closing date
- Oct 10, 2016
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Job Details
Scientist, Cell Culture & Automation - Molecular Discovery-MOL000351
Description
Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.
Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.
Description:
A highly motivated candidate is sought to join the Protein Science group in the Department of Structural Chemistry and Chemical Biotechnologies. This group utilizes multidisciplinary approaches to understand protein structure, function, and dynamics of novel targets in preparation for their advancement into our drug discovery pipeline. The job requires the candidate to work in cross-functional teams to understand the cell culture needs of different functional areas and provide starting materials for recombinant protein purification. Specific projects will involve cross-functional collaborations across diverse therapeutic areas that target proteins and pathways in oncology, immunology, cardiometabolic diseases, infectious disease, and neuroscience. This is a basic research position that requires critical thinking, flexibility, multitasking, and the ability to bring in new technologies to enable expression of difficult to produce proteins.
Responsibilities:
- Contribute to Protein Science efforts in standard and high throughput expression screening and characterization of various recombinant protein targets including membrane proteins and multi-protein complexes to enable generation of high quality proteins for screening and structure determination.
- Independently perform experiments and manage routine cell maintenance activities with careful attention to detail and documentation.
- Work with CRO’s to outsource routine DNA production and protein expression work.
- Present data at team and group meetings.
- Excellent written and oral skills needed.
- Accomplish goals under project team timelines.
Qualifications
Education Requirements:
- Qualified candidates will have a BS with 2-4 years or MS with 1-3 years in Biochemistry, Protein engineering, Molecular/Structural biology, Biophysics or equivalent education.
Basic Requirements:
- Preference will be given to candidates with technical expertise in microbial and eukaryotic cell culture, automated protein expression and cell culture strategies, VLP production, membrane preparation and protein characterization methodologies.
- Demonstrated proficiency in execution and troubleshooting of microbial and eukaryotic expression of recombinant proteins using traditional or Wave bioreactor and/or shake flask up to 10L scale required.
- Ability to operate, program and troubleshoot automated systems such as Tecan, Hamilton STAR or Biomek FX liquid handlers, Ambr microbioreactor and/or other integrated automated systems is highly preferred.
- Strong skills in use of computational tools for molecular biology, automation control, LIMS and database management
- Experience with analytical techniques such as SDS-PAGE, Western blot and LC-MS desired.
- Experience in protein biochemistry including but not limited to protein engineering and design, protein purification and biophysical characterization is a plus.
- The successful candidate must be highly organized, motivated, work independently in a collaborative team-oriented setting, and have strong analytical, organizational, and communication skills.
Our employees are the key to our company’s success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Our Company’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. If you need an accommodation for the application process please email us at staffingaadar@merck.com.
Search Firm Representatives Please Read Carefully:
Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.
For more information about personal rights under Equal Employment Opportunity, visit:
EEOC Poster
EEOC GINA Supplement
Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.
Job: Molecular Discovery - DPS
Job Title:Scientist, Molecular Discovery
Primary Location: NA-US-PA-West Point
Employee Status: Regular
Travel: Yes, 5 % of the Time
Number of Openings: 1
Hazardous Materials: Radioactivity and drug like compounds
Company Trade Name:Merck
Description
Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.
Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.
Description:
A highly motivated candidate is sought to join the Protein Science group in the Department of Structural Chemistry and Chemical Biotechnologies. This group utilizes multidisciplinary approaches to understand protein structure, function, and dynamics of novel targets in preparation for their advancement into our drug discovery pipeline. The job requires the candidate to work in cross-functional teams to understand the cell culture needs of different functional areas and provide starting materials for recombinant protein purification. Specific projects will involve cross-functional collaborations across diverse therapeutic areas that target proteins and pathways in oncology, immunology, cardiometabolic diseases, infectious disease, and neuroscience. This is a basic research position that requires critical thinking, flexibility, multitasking, and the ability to bring in new technologies to enable expression of difficult to produce proteins.
Responsibilities:
- Contribute to Protein Science efforts in standard and high throughput expression screening and characterization of various recombinant protein targets including membrane proteins and multi-protein complexes to enable generation of high quality proteins for screening and structure determination.
- Independently perform experiments and manage routine cell maintenance activities with careful attention to detail and documentation.
- Work with CRO’s to outsource routine DNA production and protein expression work.
- Present data at team and group meetings.
- Excellent written and oral skills needed.
- Accomplish goals under project team timelines.
Qualifications
Education Requirements:
- Qualified candidates will have a BS with 2-4 years or MS with 1-3 years in Biochemistry, Protein engineering, Molecular/Structural biology, Biophysics or equivalent education.
Basic Requirements:
- Preference will be given to candidates with technical expertise in microbial and eukaryotic cell culture, automated protein expression and cell culture strategies, VLP production, membrane preparation and protein characterization methodologies.
- Demonstrated proficiency in execution and troubleshooting of microbial and eukaryotic expression of recombinant proteins using traditional or Wave bioreactor and/or shake flask up to 10L scale required.
- Ability to operate, program and troubleshoot automated systems such as Tecan, Hamilton STAR or Biomek FX liquid handlers, Ambr microbioreactor and/or other integrated automated systems is highly preferred.
- Strong skills in use of computational tools for molecular biology, automation control, LIMS and database management
- Experience with analytical techniques such as SDS-PAGE, Western blot and LC-MS desired.
- Experience in protein biochemistry including but not limited to protein engineering and design, protein purification and biophysical characterization is a plus.
- The successful candidate must be highly organized, motivated, work independently in a collaborative team-oriented setting, and have strong analytical, organizational, and communication skills.
Our employees are the key to our company’s success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Our Company’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. If you need an accommodation for the application process please email us at staffingaadar@merck.com.
Search Firm Representatives Please Read Carefully:
Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.
For more information about personal rights under Equal Employment Opportunity, visit:
EEOC Poster
EEOC GINA Supplement
Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.
Job: Molecular Discovery - DPS
Job Title:Scientist, Molecular Discovery
Primary Location: NA-US-PA-West Point
Employee Status: Regular
Travel: Yes, 5 % of the Time
Number of Openings: 1
Hazardous Materials: Radioactivity and drug like compounds
Company Trade Name:Merck
Company
Our vision is to make a difference in the lives of people globally through our innovative medicines, vaccines, biologic therapies, consumer health and animal products. We aspire to be the best healthcare company in the world and are dedicated to providing leading innovations and solutions for tomorrow.
We have made it our mission to provide innovative, distinctive products and services that save and improve lives, satisfy customer needs and to be recognized as a great place to work
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