Principal Scientist - Pharmacology Job

2 days left

West Point PA
Sep 22, 2016
Oct 24, 2016
Organization Type
Principal Scientist - Pharmacology-PHA001337


Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

The Department of Pharmacology at Merck Research Laboratories is seeking a Principal Scientist to lead a group of researchers dedicated to the discovery of novel anti-infective drugs. The primary responsibilities of the group are to design, develop, and execute in vitro assays to evaluate and characterize drug candidates from antibacterial, antifungal, antiviral and vaccine development programs.

The successful candidate will:

- Develop and manage a group of associate scientists with expertise in assays measuring bacterial/fungal phenotypic changes or growth inhibition, inhibition of viral replication and virus neutralization

- Provide functional expertise in the areas of anti-infective assay development and execution

- Identify, validate and integrate new technologies or methodologies, as needed, to address questions related to drug discovery programs and projects.

- Set goals and objectives (e.g.,program/project goals and development of new capabilities) in collaboration with supervisor and key stakeholders

- Align and manage team members and reports to execute on departmental priorities

- Optimize efficiency and productivity (e.g., cycle time, innovation, financial stewardship, communication and collaboration) through effective management of work flow

- Evaluate outsourcing options and design work plans as appropriate

- Represent Pharmacology on program teams and provide input on the design of the program’s research operating plan and strategy

- Ensure timely communication and delivery of high-quality in vitro data to Therapeutic Area program teams

- Collaborate with other Pharmacology groups to provide the required support for drug discovery programs



- PhD in biology, biochemistry, virology, bacteriology or related discipline with a minimum of 8 years of relevant experience


- Experience in antibacterial, antifungal drug discovery; experience managing associate scientists

- Ability to understand and implement applicable regulations regarding the use of pathogens (e.g. virus, bacteria, fungi), human cell and tissue use, laboratory safety, health physics and chemical hazards in research.

- Experience in the design, development and execution of in vitro assays for anti-infective drug development programs targetting antivirals, antibacterials, antifungals, and/or vaccines

- Experience in the drug discovery and development process from screening through clinical candidate identification

- Strong collaborative skills

- Experience in the management of associate research scientists

- Skill in troubleshooting experimental design, assay development and data analysis

- Knowledge of anti-infective drug targets and the context of pharmacologic intervention


- Experience in antiviral drug discovery, vaccine development

Our employees are the key to our company’s success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Our Company’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. If you need an accommodation for the application process please email us at

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Job: Pharmacology - DPS

Job Title:Prin. Scientist, Pharmacology

Primary Location: NA-US-PA-West Point

Employee Status: Regular

Travel: No

Number of Openings: 1

Shift (if applicable): N/A

Company Trade Name:Merck