Postdoctoral Position in Carbohydrate and Glycoconjugate Chemistry

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Sep 28, 2016
Oct 26, 2016
Organization Type
University and College
Full Time
Postdoctoral position (full time) at the Institute of Molecular Pharmacy, University of Basel (main host), and Polyneuron Pharmaceuticals AG, Basel (collaboration partner) is available immediately (standard Swiss postdoc salary). The contract for the position will be for one year with a possible extension.

The postdoc will work on a project aiming at the development of a new therapeutic approach for inflammatory peripheral neuropathies. Our novel approach is based on a glycoconjugate platform that enables the rational design of antigen-specific autoantibody scavengers. The platform's focus is on immune-mediated diseases associated with anti-glycan antibodies such as anti-MAG neuropathy, multifocal motor neuropathy, and Guillain-Barré syndrome.


We have laboratories with state-of-the-art equipment for synthesis, analysis, molecular modelling and biological evaluation of complex carbohydrates and glycoconjugates. The applicant will work in the following areas:

  • Chemical synthesis of carbohydrate and mimetics
  • Multi-step chemical (or chemo-enzymatic) synthesis of complex oligosaccharides
  • Synthesis of glycopolymers


The highly motivated applicant should have a Ph.D. in the field of glycochemistry. Sound know-how in complex oligosaccharide synthesis and analytical methods (MS, NMR, HPLC) are essential for the success of the project. Experience in chemo-enzymatic synthesis of carbohydrates, glycoconjugate synthesis and/or peptide synthesis would be desirable. Besides these expertises and a strong interest in drug R&D, good knowledge of the English language is a prerequisite. The successful applicant has to be proactive, well organized, and possess excellent communication skills in order to collaborate efficiently with the academic research group and the spin-off.

We offer you

The Institute of Molecular Pharmacy, headed by Prof. Beat Ernst, has a successful track record in the development of glycomimetics for therapeutic applications. Together with the University's spin-off Polyneuron Pharmaceuticals AG, we are offering a postdoctoral position in our highly interdisciplinary team.


If you fulfill the above-mentioned criteria, please send your e-application (cover letter, CV, and list of publications) to Prof. Beat Ernst (