Postdoctoral Position in Carbohydrate and Glycoconjugate Chemistry
The postdoc will work on a project aiming at the development of a new therapeutic approach for inflammatory peripheral neuropathies. Our novel approach is based on a glycoconjugate platform that enables the rational design of antigen-specific autoantibody scavengers. The platform's focus is on immune-mediated diseases associated with anti-glycan antibodies such as anti-MAG neuropathy, multifocal motor neuropathy, and Guillain-Barré syndrome.
We have laboratories with state-of-the-art equipment for synthesis, analysis, molecular modelling and biological evaluation of complex carbohydrates and glycoconjugates. The applicant will work in the following areas:
- Chemical synthesis of carbohydrate and mimetics
- Multi-step chemical (or chemo-enzymatic) synthesis of complex oligosaccharides
- Synthesis of glycopolymers
The highly motivated applicant should have a Ph.D. in the field of glycochemistry. Sound know-how in complex oligosaccharide synthesis and analytical methods (MS, NMR, HPLC) are essential for the success of the project. Experience in chemo-enzymatic synthesis of carbohydrates, glycoconjugate synthesis and/or peptide synthesis would be desirable. Besides these expertises and a strong interest in drug R&D, good knowledge of the English language is a prerequisite. The successful applicant has to be proactive, well organized, and possess excellent communication skills in order to collaborate efficiently with the academic research group and the spin-off.
We offer you
The Institute of Molecular Pharmacy, headed by Prof. Beat Ernst, has a successful track record in the development of glycomimetics for therapeutic applications. Together with the University's spin-off Polyneuron Pharmaceuticals AG, we are offering a postdoctoral position in our highly interdisciplinary team.
If you fulfill the above-mentioned criteria, please send your e-application (cover letter, CV, and list of publications) to Prof. Beat Ernst (firstname.lastname@example.org).