Senior Scientist, Immuno-Oncology Job

3 days left

Boston MA
Oct 12, 2016
Oct 28, 2016
Organization Type
Senior Scientist, Immuno-Oncology-BIO004694


Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

We are seeking a highly motivated and skilled research associate to join our Immuno-Oncology team at Merck, Boston. The successful candidate will be responsible for validating novel Immuno-oncology targets and contributing to large molecule drug discovery programs. Responsibilities include the development and execution of experimental strategies to define biomarkers, mechanism of action and mechanism of resistance of Immuno-oncology therapeutic agents. S/he will perform in vitro and ex vivo experiments to determine the functional effect of candidate target activation/inhibition by using a variety of assays to interrogate immune end-points. Candidate is expected to keep abreast of published scientific literature and present his/her data at internal group meetings.



- BS in Science with 10 + years of experience in preclinical drug discovery/development
- MS with 7+ years of experience in preclinical drug discovery/development
- Ph.D. in tumor immunology with at least 3 years of post-doctoral experience.


- Candidate should have experience in primary immune cell isolation and stimulation, proliferation and apoptosis assays, immunoassay techniques/platforms (e.g. Western, ELISA, Mesoscale), as well as RT-PCR.
- Candidate should be competent in standard scientific software used for data analysis (e.g. Microsoft Excel) as well as Microsoft Word and PowerPoint.
- Candidate should be a strong team player with excellent oral and written communication skills and with a demonstrated ability to work independently to design experiments, interpret data, troubleshoot, and suggest next steps.
- Candidate must have expertise in developing in vitro and in vivo assays to investigate immune function and possess a deep knowledge of technologies commonly used to assess immune endpoints.


- Experience with multi-parameter FACS.
- Experience in preclinical development of drugs against immuno-oncology targets
- Understanding of the target identification/validation and overall preclinical drug development process

Our employees are the key to our company’s success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Our Company’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. If you need an accommodation for the application process please email us at

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Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

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Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Job: Biology-Discovery

Job Title:Sr. Scientist, Biology-Discovery

Primary Location: NA-US-MA-Boston

Employee Status: Regular

Travel: No

Number of Openings: 1

Shift (if applicable): N/A

Hazardous Materials: SEB, radiation

Company Trade Name:Merck