Research Fellow: Looking at the effects of exercise on structural and electrical modelling in right

2 days left

United Kingdom
Oct 17, 2016
Oct 28, 2016
Organization Type
University and College
Full Time
Are you an ambitious researcher looking for your next challenge? Do you have an established background in cardiac imaging and computational modelling? Do you want to further your career in one of the UKs leading research intensive Universities?

Looking at the effects of exercise on structural and electrical modelling in right heart failure, we will determine whether exercise training can reduce arrhythmias.

After taking measurements of the function of the heart in an experimental model, we will use the data collected to develop computer models which will be used to identify whether (and how) changes to the heart brought about by exercise training are beneficial for reducing arrhythmias. This will allow us to determine whether exercise is an effective therapy for those with right heart failure, in terms of reducing arrhythmias and sudden deaths, and may also help us to identify whether exercise is beneficial for those with other forms of heart failure

You will have a PHD (or be close to completion) in biology, physiology or a closely allied discipline. You will also have experience of the monocrotoline model of pulmonary hypertension-induced right heart failure, optical imaging of excitation in the heart, ex-vivo diffusion tensor MRI of the heart and analysis of these data (including fibre tractography), and computational finite-difference modelling of excitation in the heart (where the structural component is built from DT-MRI data).