Associate Principal Scientist – Sterile Product and Analytical Development, Bioprocess...

Associate Principal Scientist – Sterile Product and Analytical Development, Bioprocess Development-BIO004695

Description

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.


The Sterile Product and Analytical Development department in in Bioprocess Development is seeking a talented and motivated scientist with solid experience in analytical characterization of therapeutic proteins. As an Associate Principal Scientist, you will hold a laboratory-based scientific role in a fast-paced, multidisciplinary team environment. The role is tasked with solving complex analytical problems related to development of protein therapeutics.

Major responsibilities include:

- Conduct forced degradation studies to assist drug candidate selection, investigate the degradation pathways of protein products, evaluate stability-indicating capabilities of analytical methods, and demonstrate product comparability;

- Perform product impurity characterization including impurity isolation and testing;

- Responsible for development, execution, and documentation of forced degradation and impurity characterization studies;

- Interface with other functional areas for study design, coordination of analytical testing, and discussion of scientific results;

- Present results and scientific findings at group, project team, and departmental meetings.

Qualifications

Education:

- A Ph.D. degree in analytical chemistry, biochemistry, or a closely-related field with a minimum of 4 years of biotech / pharmaceutical experience.

Required:

- More than 2 years of experience in analytical development of protein therapeutics focusing on forced degradation studies of biopharmaceutical products;

- Understanding of protein structure, post-translational modifications, and their relationships to protein functions and stabilities;

- Hands-on experience with Agilent HPLC, Waters HPLC/UPLC and Beckman CE instrumentations;

- Established working knowledge of protein analysis using analytical techniques including UV spectroscopy, Ellman’s test, RP, HIC, IEX, SEC and CE-SDS;

- Familiar with Chemstation, Empower, OpenLab, and ELN software;

- Detail oriented and effective organizational, multi-tasking, oral / written communications skills.

Preferred:

- Knowledge of regulatory and quality guidelines.

Our employees are the key to our company’s success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Our Company’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. If you need an accommodation for the application process please email us at staffingaadar@merck.com.

Search Firm Representatives Please Read Carefully:

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster

EEOC GINA Supplement​



Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.


Job: Biologics, Vaccines, Analytical Formulat

Job Title:Assoc Prin. Scientist, Bio & Vacc Formul

Primary Location: NA-US-NJ-Kenilworth

Employee Status: Regular

Travel: Yes, 5 % of the Time

Number of Openings: 1

Shift (if applicable): N/A

Hazardous Materials: Chemicals

Company Trade Name:Merck