Senior Scientist - Bioassay Job

Senior Scientist - Bioassay-BIO004802

Description

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.


We are seeking a highly motivated senior scientist to join our potency & analytical testing team within the Biologics and Vaccines Analytical Biologics BioProcess organization at the Merck-Kenilworth campus. The qualified candidate will be responsible for the development and qualification of assays for various protein therapeutics. Position responsibilities include development of multiple assays to assess biological activity and characterize therapeutic proteins for extended characterization, QC lot release, and stability studies, providing oversight to CROs, and transfer of assays into GMP and QC laboratories.

The successful candidate will work as part of an extended team and have a detailed knowledge of potency assays and functional characterization of therapeutic proteins through all stages of development, with a focus on assays for Fc analysis for mAb therapeutics including cell-based assays for ADCC and CDC. Additional responsibilities will include development of surface plasmon resonance (Biacore)-based assays to measure target binding affinity, FACS analysis, and development of assays for bispecifics, nanobodies, insulins and insulin-like molecules. The senior scientist will also be expected to prepare technical reports and submission documents, trouble shoot assays, and effectively communicate to scientific audiences including senior management.

Qualifications

Education:

- MS with a minimum of 6 years of therapeutic protein drug development experience OR PhD with therapeutic protein drug development experience.

Required:

- Critical skills include detailed experience in immunoassay development, tissue culture, FACS, Biacore, and cellular assay development including antibody dependent cellular cytotoxicity and complement dependent cytotoxicity assays supporting all stages of therapeutic protein development.

- Must have experience trouble-shooting and improving methods and excellent oral and written communication skills including preparation of technical reports and health authority submission documents.

- Ability to effectively work independently (minimal direction) and within project teams is critical.

Preferred:

- Ideal candidate will have developed assays for mAbs, nanobodies, peptides, insulins or insulin variants, and bispecifics.

- Experience with assay qualification / validation is desired.

Our employees are the key to our company’s success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Our Company’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. If you need an accommodation for the application process please email us at staffingaadar@merck.com.

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Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

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Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.


Job: Biologics, Vaccines, Analytical Formulat

Job Title:Sr. Scientist, Bio & Vacc Formul

Primary Location: NA-US-NJ-Kenilworth

Employee Status: Regular

Travel: No

Number of Openings: 1

Hazardous Materials: Biological samples, including human cell lines.

Company Trade Name:Merck