Senior Scientist, Sterile Formulation Development Job

Senior Scientist, Sterile Formulation Development-PRE000588

Description

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its 125-year legacy. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

The successful candidate will be responsible for designing and developing sterile products for small molecule, peptide, oligonucleotide, and biologic drugs for injectable and ophthalmic routes of administration. Primary duties to support both early and late stage development candidates will include screening and developing robust drug product composition, developing scalable process and defining primary packaging. The candidate will also be responsible for supporting appropriate compatibility characterization to enable processing of drug product and dosage administration in toxicology and clinical study.

The candidate will build deep fundamental knowledge around the drug product and document experimental findings and conclusions in formulation development reports. Active participation and leadership on formulation development teams and interfacing and collaborating with key stakeholders to drive project milestones will be required. The candidate should be willing to take initiative, motivated to excel, have a strong technical background, have excellent communication and interpersonal skills, ability to multi-task, mentor fellow scientists, and a strong desire to learn and contribute.

Qualifications

Education:

- Ph.D. Degree in Chemical Engineering, Pharmaceutics, Pharmaceutical Chemistry, Pharmaceutical Sciences, Chemistry, Biochemistry or related field.

Required:

- 0-4 years of work experience in sterile product development/parenteral drug delivery.

- A strong background in drug delivery and/or complex formulation development, lyophilization process development and/or intermediate to large modality characterization

- Fair understanding of the requirements for developing sterile dosage forms (liquid, lyophilized) including composition (solubilization and stabilization approaches) and process (aseptic, terminally sterilized).

Preferred:

- Course work in physiology, pharmacokinetics, biochemistry, chemical kinetics, Transport phenomenon, polymer chemistry, physical pharmacy is highly desirable.

- Experience in formulation/process, definition of critical attributes for process scale-up, analytical development and CMC filing for sterile dosage forms including ocular dosage forms, peptide therapeutics, and non-conventional drug delivery technologies (e.g. emulsions, suspensions, injectable depot)

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need an accommodation for the application process please email us at staffingaadar@merck.com.

Search Firm Representatives Please Read Carefully:

Merck is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

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Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.


Job: Preclinical Dev Generic

Job Title:Sr. Scientist, Preclinical Dev.

Primary Location: NA-US-NJ-Kenilworth

Other Locations: NA-US-PA-West Point

Employee Status: Regular

Travel: No

Number of Openings: 1

Hazardous Materials: Beta lactam antibiotics or high potency compounds

Company Trade Name:Merck