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PhD Studentship: Tailoring nano-clay gels for early stage regeneration following severe trauma

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Following severe trauma successfully fighting infection and kick starting the repair process early on are vital for improving subsequent outcomes and rehabilitation. However the challenging scenarios where such trauma is most likely to occur, such as on a battlefield limit, the use of high tech regenerative medicine strategies.

In Southampton we have been pioneering the application of nanoclay gels in regenerative medicine based on their ability to bind growth factors to stimulate stem cells. We have exciting new evidence for the ability of clay gels to enhance wound healing without relying on growth factors or other drugs. We also have promising data that nanoclay gels can carry antimicrobials to prevent infection.

This project will seek to build on these exciting observations to develop a sprayable regenerative matrix to stimulate early wound healing following severe trauma.

You will work in a vibrant, multidisciplinary team between the Faculties of Medicine and Engineering at the University. You need to have a 2:1 or equivalent and ideally you will have a background in bioengineering, but we encourage applications from talented individuals with backgrounds in biology, physics and chemistry.

This PhD project will be funded as part of the UK governments new Industrial Strategy. The scholarship will cover full UK fees and a stipend of between £16k and £18k per year depending on academic qualifications.

If you wish to discuss any details of the project informally, please contact Nick Evans, Bioengineering research group, Email: n.d.evans@soton.ac.uk, or Dario Carugo, Email: D.Carugo@soton.ac.uk Tel: +44 (0) 238120 3293 or 023 8059

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