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PhD studentship: Mutation burden of narrowband UVB

Employer
Global Academy Jobs
Location
United Kingdom
Closing date
Jul 7, 2017

Job Details

Lead Institute / Faculty: University of Southampton, Medicine

Main Supervisor: Prof Eugene Healy

Other members of the supervisory team: Prof John Holloway, Dr Mat Rose-Zerilli

Duration of the award: 3 years full time PhD studentship

Full time or part time: Full time

Project description: Ultraviolet radiation (UV) in sunlight is a “double-edged sword”; exposure to UV causes genetic mutations in skin leading to development of skin cancer but, conversely, UV promotes vitamin D synthesis and is also used to treat skin diseases, including psoriasis. This study will use next generation DNA sequencing to investigate the mutational load in skin from UV exposure in relation to skin cancer development, thus informing on safe UV exposure levels in a unit which has significant experience in this type of research. The applicant will receive training in genetics/UV/skin carcinogenesis under the supervision of a team comprising Prof Eugene Healy (Professor of Dermatology, Clinical and Experimental Sciences, University of Southampton), Prof John Holloway (Associate Dean for Research, Genetics/Human Development and Health, University of Southampton), Dr Mat Rose-Zerilli (John Goldman Fellow, Cancer Sciences, University of Southampton) and will undertake the research in the Faculty of Medicine, University of Southampton.

Please contact:  Prof Eugene Healy; ehealy@soton.ac.uk

Person Specification: See below.

Candidates must hold, or expect to obtain in the current year, a 1st or 2:1 degree or Masters degree in a relevant discipline, e.g. in molecular biology, genetics, cancer, biochemistry, bioinformatics, etc.

The successful candidate is likely to have the following qualifications:

  • A 1stor 2:1 degree in a relevant discipline and/or second degree with a related Masters

Funding information: PhD studentship is funded by the Psoriasis Association, a Registered Charity, as a means to understanding UV exposure risks because UV is used in the treatment of psoriasis. UK/EU fees funded only.

Administrative contact and how to apply:

You should enter “Prof Eugene Healy” as your proposed supervisor. To support your application provide an academic CV (including contact details of two referees), official academic transcripts and a personal statement (outlining your suitability for the studentship, what you hope to achieve from the PhD and your research experience to date).

Informal enquiries relating to the project or candidate suitability should be directed to Prof Eugene Healy (ehealy@soton.ac.uk).

Interview date:  To be advised (mid-late July / early August)

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