Research Technician

Job Purpose Development of HLA-C restricted TCR gene therapy for patients with cytomegalovirus infection

Professor Paul Moss is seeking a highly motivated individual for a band 500 research technician position to support a post-doctoral research fellow in his CMV and Transplant research group. The successful candidate will work on developing a HLA-C restricted CD8+ T cell immunotherapy to treat CMV mediated disease in the post-hematopoietic transplant setting. This post is funded by a ‘MRC Confidence in Concept’ fund and is available for 12 months in the first instance. The role holder will assist in the in vitro transduction and molecular cloning work required to generate CD8+ T cells expressing a unique CMV-specific ‘T cell receptor’ (TCR) for testing against CMV infected cells.

  Person Specification • Have or studying for an MRes or equivalent qualification in immunology or an appropriate subject
• BSc degree or equivalent professional qualification in an appropriate subject at 2:1 or above
• GCSE (A*- C) or equivalent in science and mathematics
• In-depth practical knowledge of technical and scientific methods stated above and Good Laboratory Practice gained through extensive experience and formal qualification
• Extensive experience of similar laboratory based work
• Positive service attitude and shows courtesy in dealing with others
• Ability to organise and manage own work load and demonstrate flexibility in terms of work practices/requirements
• Ability to work under minimal supervision but function as part of a team
• Knowledge of current relevant H&S policies
• Proficiency in commonly used software packages