Skip to main content

This job has expired

Research Associate in Mammalian Cell Competition

Employer
Global Academy Jobs
Location
United Kingdom
Closing date
Jul 5, 2017

Job Details

 

Two Wellcome Trust funded postdoc positions in mammalian cell competition are available to join the group of Eugenia Piddini at the School of Cellular and Molecular Medicine, University of Bristol, UK (http://research-information.bristol.ac.uk/en/persons/eugenia-piddini(d9edf159-92ca-4b42-8bd6-6dbe1de23195).html).

 

The Piddini group studies the mechanisms and function of cell competition and investigates how cell competition can be harnessed to identify novel therapeutic opportunities in cancer and in regenerative medicine. Using epithelial-derived cell lines and mouse primary airway epithelial cells, our group has recently shown that p53 activation induces crowding-hypersensitivity and leads to the elimination of cells by neighbouring cells with low p53 levels. We are now seeking to appoint two outstanding post-docs to expand this work in two directions:

 

1) Investigate the mechanisms of mechanical cell competition. For this project we are seeking applicants with broad expertise in mammalian cell biology, molecular biology and signal transduction. Prior expertise in the field of mechano-sensing, mechano-transduction and cytoskeletal organisation and remodelling would be a definite plus.

 

2) Investigate how to exploit cell competition to improve engraftment and repopulation of the airways for regenerative medicine approaches. This project will include both in vitro and in vivo work, using mouse models. The in vivo work will be done in collaboration with the group of Emma Rawlins at the University of Cambridge. For this project we are seeking applicants with expertise in mouse models (including preferably procedures in vivo) and cultures of primary cells.

 

Applicants should be highly motivated and have a substantial track record of productivity and international experience. They should have a PhD in a relevant subject area, or be close to completion of their degree.

 

Applications should include a CV and a brief statement outlining key areas of expertise, reasons why you would like to join the group and preferred project. Informal enquiries can be addressed to Dr Eugenia Piddini: eugenia.piddini@bristol.ac.uk.

 

The funds for the two posts are available for 2 years in the first instance.

 

 

The University is committed to creating and sustaining a fully inclusive culture.  We welcome applicants from all backgrounds and communities.

Company

Global Academy Jobs works with over 250 universities worldwide to promote academic mobility and international research collaboration. Global problems need international solutions. Our jobs board and emails reach the academics and researchers who can help.

"The globalisation of higher education continues apace, driving in turn the ongoing development of the global knowledge economy, striving for solutions to the world’s problems and educating a next generation of leaders and contributors."

Company info
Website

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert