Research Fellow (TAKEDA)

Job Purpose

This post will involve engagement in a research programme focussed upon understanding novel mechanisms that contribute to the development of human fatty liver disease, and is funded by Takeda/Millennium pharmaceuticals. This research collaboration aims to gain a better understanding of disease by studying human tissue and cells derived from livers and blood of patients ex vivo. This work will support on-going programs at Takeda that aim to develop therapeutic treatment options for NASH patients. In addition, studies will be performed to delineate further signalling pathways that are thought to play a role in disease progression to allow identification of molecular targets for intervention. The appointed post doctoral fellow would be expected to undertake a specified range of laboratory investigations, to analyse and interpret data and to assist with creation of reports for returning to the funder.

Person Specification

• First degree in a subject related to biomedical science or metabolism and a higher degree ideally relevant to the key research area of liver biology and human liver disease, inflammation and/or metabolism. Ideal candidates will also demonstrate at least some of the following :
• Previous experience in mammalian cell culture, histology and/or metabolic analysis
• Previous experience of immunoassays is desirable
• Experience working within the remit of heath and safety legislation and familiarity with ethical use of human tissue is desirable
• Previous experience drafting papers for publication
• Previous experience working with research students
• Ability to communicate complex information clearly
• Proven experience in developing new techniques or troubleshooting experimental design
• Ability to assess resource requirements and use resources effectively
• Understanding of and ability to contribute to broader management/administration processes