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Post-doctoral position - Epigenomic and transcriptomic regulations in obesity-related diseases

Employer
Global Academy Jobs
Location
France
Closing date
Oct 16, 2017

Job Details

INSERM U1011 “Nuclear receptors, cardiovascular diseases and diabetes”

Lille, France

Context: Our laboratory, which is part of the European Genomic Institute for Diabetes (EGID, Lille, France), studies obesity-related diseases including diabetes and atherosclerosis. We rely on long-lasting experiences in biochemistry, molecular biology and functional genomics together with access to state-of-the-art technologies to investigate transcriptional regulatory programs involving nuclear receptors in key metabolic organs and inflammatory cells (Lien et al. J Clin Invest 2014; Dubois-Chevalier J et al. Genome res 2017; Chinetti-Gbaguidi G et al. Circ res 2017 ; Lefebvre al. JCI Insight 2017).

Project: Inflammatory cells from human cohorts of patients at risk for cardiovascular diseases will be characterized using both epigenomic and transcriptomic profiling. Using a combination of in-vitro cellular and animal models, we will interfere with epigenomic/transcriptomic events which have been associated with occurrence of cardiovascular events.
 
For further details please contact Drs J. Eeckhoute (jerome.eeckhoute@inserm.fr) or P.Lefebvre (philippe-claude.lefebvre@inserm.fr).

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