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PhD Studentship: Hyperpolarized xenon MRI for assessment of gas exchange and perfusion limitation i

Employer
Global Academy Jobs
Location
United Kingdom
Closing date
Apr 2, 2018

Job Details

Details

Hyperpolarised xenon MRI can provide novel insight in to ventilation, perfusion and alveolar-capillary gas exchange. Our pilot data with the method suggest it has sensitivity to provide quantitative information that can help distinguish subgroups of pulmonary hypertension eg distinguish interstitial changes in PH-SSc and hemodynamic changes related to post-capillary disease in PVOD.

In this project we will recruit a non-clinical MRI scientist PhD student to work on further development of dissolved phase xenon imaging techniques for quantitative assessment of alveolar-capillary gas exchange in PH. We will then evaluate the methods alongside established proton MRI methods for contrast enhanced perfusion imaging in cohorts of patients recruited from the SPVDU with subgroups of PH.

The student will be a physicist/engineer based in the POLARIS group under the supervision of Jim Wild and will liaise closely with the SPVDU and clinical fellows working in this field.

You will participate and develop in the exciting Donald Heath pulmonary hypertension research programme. This multi-disciplinary programme combines clinicians and clinician scientists with biologists, physicists and engineers based at the University of Sheffield and Royal Hallamshire Hospital, Sheffield towards the better understanding of the mechanisms driving Pulmonary Hypertension, and improved patient care. The successful candidate will undertake research towards a PhD in the Department of Infection, Immunity & Cardiovascular Disease, Faculty of Medicine Dentistry & Health. There is 1 fully funded PhD studentship available to work on one of the projects listed here - https://donaldheath.org/home/current-opportunities/

Interested candidates are encouraged to make contact with the primary supervisor to discuss their application. Further project details and additional Donald Heath PhD application form are available from - https://donaldheath.org/home/current-opportunities/

 

Funding Notes

This PhD is fully funded with a stipend of £19,057 for up to 3 years.

 

Enquiries:

Interested candidates should in the first instance contact the named PhD supervisor on the project of interest, or the Programme Director Dr Allan Lawrie (0114 215 9536 / a.lawrie@sheffield.ac.uk)

 

Entry Requirements:

Candidates must have a first or upper second-class honors degree. Completion of a Masters degree is highly desirable.

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