Researcher - Manufacturing (Nano) of immunosensors
The applicant will work in a clean room environment and in a chemistry laboratory in order to produce the planned samples. He will also be in charge of the meetings and talks linked to the progress of the project. The applicant will work on the ImmuNanocaps project (ANR funding) in order to fabricate an immunosensor that aims to diagnose viral illnesses. One of the milestones will be to increase the detection limit.
The IJL a joint research unit (UMR 7198) of CNRS and Université de Lorraine. It is linked to the Institute of Chemistry of CNRS. Its research activities are led by 23 research group sorganized into 4 scientific departments :
- Physics of Matter and Materials Department
- Chemistry and Physics of Solids and Surfaces Department
- Materials Science and Engineering - Metallurgy Department
- Nanomaterials, Electronics and Living Systems Department
They are supported by 8 competence centers and 3 support services.
The research will take place within the 405 group (micro and nano systems) on the ANR project Immunanocaps.
Summary of project
The immunosensors based on electrochemical transducers have gained great attention for clinical diagnostics, since they present simplified instrumentation, high sensitivity and low cost. Over time, the infection risk of vector-borne diseases in southern Europe and in particular along the Mediterranean coast should increase considerably. The project focuses on the use of innovative conductive nanocapsules for the development of sensitive label-free electrochemical immunosensors for the detection of infectious vector-borne diseases such as West Nile virus (WNV) and Dengue virus (DENV). The advantage of the nanocapsules, developed and produced at IJL in Nancy, is the possibility to tailor their size and composition to provide optimal conditions for the compounds to encapsulate or to graft. The DCM partner at Grenoble will be in charge of the electrochemical functionalization of conductive nanocapsules with functional polymer and of the development of label-free electrochemical immunosensors.
- The applicant should be an expert in clean room work (Ebeam lithography, and sputtering deposition) and should have a thorough knowledge in chemistry.
- A physicist profile is needed.
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