Research Fellow in High-Throughput Synthesis and Chemical Biology

Are you an ambitious researcher looking for your next challenge?

Do you have an established background in chemical biology and synthetic organic chemistry?

Do you want to further your career in one of the UK's leading research intensive universities?

We are looking for an exceptional researcher to work on our project 'Autonomous Discovery of Functional Small Molecules', with Professor Adam Nelson and Dr Stuart Warriner, in alignment with Professor Nelson's EPSRC Established Career Fellowship. The aim of the research programme is to develop and exemplify new methods that may be exploited in the autonomous discovery of bioactive small molecules. The programme builds on activity-directed synthesis, our novel approach that enables the discovery of bioactive small molecules. This approach exploits synthetic methods with inherently unpredictable outcomes to enable the discovery of unexpected chemotypes in parallel with associated synthetic routes.Within the role, you will develop and integrate high-throughput synthetic and biological methods, working in collaboration with chemists and biologists. You will exemplify the resulting technology platform, demonstrating using exemplar target proteins its value in facilitating disruptive molecular discovery. The position will additionally provide tailored opportunities to support your professional development, for example in grant-writing, teaching and networking.

You will have a PhD in chemical biology or bioactive molecule synthesis, or a closely aligned discipline, together with experience of bioactive small molecule synthesis, and the ability to perform high-throughput synthesis and chemical biology research. You'll also have excellent communication skills and the ability to work under pressure and meet deadlines.

To explore the post further or for any queries you may have, please contact: Professor Adam Nelson, Professor of Chemical Biology Tel: +44 (0)113 343 6502, email: A.S.Nelson@leeds.ac.uk