PhD Studentship - Chemical Biology: Elucidating the mode of action of a novel nematicide on plant p

United Kingdom
Mar 24, 2016
Oct 28, 2016
Organization Type
University and College
Full Time

PhD Studentship – Chemical Biology: Elucidating the mode of action of a novel nematicide on plant parasitic nematodes

Biological Sciences Research

Location:  Highfield Campus
Closing Date:   Friday 28 October 2016
Reference:  712316BJ

PhD Supervisor: Lindy Holden-Dye, co supervisor: Vincent O'Connor

Application Deadline: open

PhD Description: 

Plant parasitic nematodes (PPNs) are microscopic worms that invade plant roots causing $157 billion of crop losses globally per annum. They are an increasing problem due to reduction in chemical nematicide use because of environmental concerns and the lack of commercially attractive cultivars with resistance. There is a pressing need to develop alternative and/or integrated strategies to tackle this continuing threat. The Holden-Dye/O'Connor group has a strong track record of working with industry to elucidate the mode of action of new chemicals and drugs. This project will explore the mode of action of a new nematicide using a range of biochemical assays, cell biology, imaging and metabolomics. Training provides an excellent pathway to a job in industry and previous PhD students working in this area have been employed by the research arm of agrochemical companies.

The project is funded for 4 years and welcomes applicants from the UK and EU who have or expect to obtain at least an upper second class degree in Biological Sciences or allied subjects. Funding will cover fees and a stipend at current research council rates of £ 14,296 per annum.

Due to funding restrictions this position is only open to UK/EU applicants

Applications for an MPhil/PhD in Biological Sciences should be submitted online at:

Please place Lindy Holden-Dye name in the field for proposed supervisor.

General enquiries should be made to Lindy Holden-Dye at:

Any queries on the application process should be made to

Applications will be considered in the order that they are received, and the position will be considered filled when a suitable candidate has been identified

The University of Southampton and the Centre for Biological Sciences both hold an Athena Swan Bronze Award, demonstrating their commitment to provide equal opportunities and to advance the representation of women in STEM/M subjects: science, technology, engineering, mathematics and medicine.   Due consideration will be given to applicants who have taken a career break.  University benefits include onsite childcare facilities, state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts. 

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