Research Fellow, Centre for Cancer Research and Cell Biology
Available in the area of apoptosis-targeted therapeutics in colorectal cancer. The post is within an internationally renowned colorectal cancer research group on a project jointly funded by the Department for Employment and Learning, Northern Ireland and Science Foundation Ireland. The research programme will be conducted in collaboration with Professor Jochen Prehn at the Royal College of Surgeons Ireland.
- To design, develop and execute experiments related to the project under the supervision of Prof Daniel Longley, in order to obtain reliable data, then evaluate and interpret the results using methodologies and techniques appropriate to the area of the research.
- Carry out analyses, critical evaluations, and interpretations using methodologies and other techniques appropriate to area of research.
- To regularly present results to the research group as part of routine peer review.
- Initiate and maintain collaborative links with various project partners.
- To write up results in a timely manner and take a leadership role in writing research manuscripts.
- To present regular progress reports on research to members of the research group and to external audiences to disseminate and publicise research findings.
- To formulate, write and submit grants for fellowship awards, project and travel support.
- To attend and present new experimental data at national and international meetings.
- Assist grant holder in the preparation of funding proposals and applications to external bodies.
- May be required to carry out undergraduate supervision within the post holder’s area of expertise and under the guidance of a member of academic staff. Assists with the supervision of postgraduate students or summer students on mini-projects, which will help develop their own supervisory skills. Carry out routine administrative tasks associated with the research project/s to ensure that project/s are completed on time and within budget. These might include organisation of project meetings and documentation, financial control, risk assessment of research activities. Read academic papers, journals and textbooks to keep abreast of developments in own specialism and related disciplines.
- Any other reasonable duties within the general ambit of the post.
Planning and Organising:
- Plan for specific aspects of research programmes. Timescales range from 1-6 months in advance and contribute to research group planning.
- Plan for the use of research resources, laboratories and workshops where appropriate.
- Plan own day-to day activity within framework of the agreed research programme.
- Plan up to a year in advance to meet deadlines for journal publications and to prepare presentations and papers for conferences.
- Coordinate and liaise with other members of the research group over work progress.
Resource Management Responsibilities:
- Ensure research resources are used in an effective and efficient manner.
- Provide guidance as required to support staff and any students who may be assisting with research.
- Take shared responsibility for the upkeep of lab equipment and replenishment of lab stocks and exercise due diligence when using equipment.
- Support the development and training of support staff and students.
Internal and External Relationships:
- Communicate openly with lab colleagues the latest research findings/results. Develop contacts with other labs within the research community at Queen’s and look to identify potential cross-discipline collaborations.
- Liaise on a regular basis with colleagues and students.
- Build internal contacts and participate in internal networks for the exchange of information and to form relationships for future collaboration.
- Join external networks to share information and ideas.
- Contribute to the School’s outreach programme by establishing links with local community groups, industries etc.
- Join national and international scientifically relevant societies.
- Have or be about to obtain a PhD in molecular biology or a related discipline.
- At least three years relevant research experience.
- Experienced in a range of molecular and cellular biology techniques, such as Western blot, immunoprecipitation, flow cytometry and apoptosis detection techniques. Experience working on apoptosis signalling (eg. FLIP and IAPs) AND with apoptosis-targeting therapeutic agents, eg. SMAC mimetics.
- Ability to contribute to broader management and administrative processes.
- Contribute to the School’s outreach programme by links with industry, patient advocacy groups etc.
- Sufficient breadth and depth of specialist knowledge in the discipline and of research methods and techniques to work within established research programmes.
- Ability to communicate complex information clearly.
- Ability to build contacts and participate in internal and external networks.
- Demonstrable intellectual ability.
- Ability to assess and organise resources.
- Team worker, highly motivated, supportive of junior colleagues within the group.
- 1st Class undergraduate degree in science or pharmacy.
- Scientific memberships eg. AACR, EACR, IACR, BACR.
- Track record of national/international collaboration.
- Experience with immune biology.
- Experience using in vivo models. Experience of epigenetic agents. Experience with fluorescent microscopy.
- Evidence of involvement in successful programmes and grant applications.
- Presentations at national/international meetings.
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