Research Fellow - Organic Synthesis of labelled molecules for application in novel magnetic resonan

Applications are invited for a two-year Synthetic Chemistry Postdoctoral Research Fellow available in the Department of Chemistry at the University of Southampton, to contribute to a pioneering programme of research in the area of long-lived states for NMR and imaging applications. The successful applicant will work closely with Professor Richard Brown, Dr Lynda Brown and Professor Malcolm Levitt as part of a collaborative team. The project will investigate the application of organic molecules labelled with stable isotopes, such as 13C and 15N, in NMR and the capacity of these compounds to support long-lived states for novel applications in NMR and imaging. The primary role of the appointee will be the design and implementation of synthetic routes towards labelled organic molecules, and tailoring probes for different applications, for example, for the study of biological systems. The appointee would also be encouraged to participate in, and learn about, the NMR experiments in collaboration with other team members.

Suitable candidates must have a strong background in synthetic organic chemistry, and be comfortable working as part of an interdisciplinary team. They should have a PhD* or possess equivalent qualifications and experience in Organic Chemistry. Relevant experience and familiarity with multi-step organic synthesis and analytical techniques (NMR, Gas or Liquid Chromatography) would be advantageous. The successful candidate should possess excellent communication skills and they will be expected to contribute to regular project meetings, and to be responsible for preparation of publications and presentations at conferences. An interest in spectroscopy or imaging is also desirable.

This fixed-term appointment is available from 01/11/2018 - for a period of 24 months in the first instance, with a possibility of extension; Informal enquiries can be made in the first instance to Professor Richard Brown (R.C.Brown@soton.ac.uk), Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ

 

For recent examples of research from the Southampton Project Team Members related to the advertised position:

1.Hill-Cousins, J. T.; Pop, I. A.; Pileio, G.; Stevanato, G.; Hakansson, P.; Roy, S. S.; Levitt, M. H.; Brown, L. J.; Brown, R. C. D., Synthesis of an Isotopically Labeled Naphthalene Derivative That Supports a Long-Lived Nuclear Singlet State. Org. Lett. 2015,17, 2150-2153.

2.Stevanato, G.; Hill-Cousins, J. T.; Hakansson, P.; Roy, S. S.; Brown, L. J.; Brown, R. C. D.; Pileio, G.; Levitt, M. H., A Nuclear Singlet Lifetime of More than One Hour in Room-Temperature Solution. Angew. Chem. Int. Ed. 2015,54, 3740-3743.

The University of Southampton is a leading UK university, ranked 8th in the UK in REF2014. The Chemistry department was ranked 6th in the UK for research intensity in REF2014.

 

Application Procedure

You should submit your completed online application form. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Elsa Samwell (Recruitment Team) on +44 (0) 23 8059 2507. Please quote reference 1041518EB on all correspondence.

*Applications will be considered from candidates who are nearing completion of a relevant PhD qualification or equivalent.  The title of Research Fellow will be applied upon completion of PhD.  Prior to the qualification being awarded the title of Senior Research Assistant will be given.

We aim to be an equal opportunities employer and welcome applications from all sections of the community. Please note that applications from agencies will not be accepted unless indicated in the job advert.