PhD Research Project: Bacterial biofilms, human health and industrial efficiency.
- Employer
- Global Academy Jobs
- Location
- United Kingdom
- Closing date
- Jan 31, 2019
View more
- Sector
- Science, Physical Sciences and Engineering, Chemical Engineering, Chemistry, Biochemistry
- Hours
- Full Time
- Organization Type
- University and College
- Jobseeker Type
- Academic (e.g. 'Lecturer')
Job Details
Biofilms are hard to remove from a variety of industrial and clinical settings and as such pose a risk to human health and industrial efficiency. However, the very factors that make biofilms problematic (resistance to antimicrobials, physical robustness) mean that they can be used as a platform for biocatalysis. We are currently interested in both desirable and undesirable biofilms, and the development of biofilms in response to environmental stimuli.
Specifically:
• What factors influence initial attachment, irreversible attachment and development of biofilm architecture?
• What regulators are involved in biofilm development?
• How can we use biofilms as biocatalysts?
The successful candidate will be able to agree a specialist research area with the supervisor once they have applied for the research.
Funding Notes
This project will be funded through the MIBTP scheme, which is a competition funding scheme. Full details on eligibility are here: https://warwick.ac.uk/fac/cross_fac/mibtp/pgstudy/phd_opportunities/application/
References
Perni S, Hackett L, Goss RJM, Simmons MJ, Overton TW (2013) Optimisation of engineered Escherichia coli biofilms for enzymatic biosynthesis of L-halotryptophans. AMB Express 3: 66
Tsoligkas, AN, Bowen, J, Winn, M, Goss, RJM, Overton, TW and Simmons, MJH. (2012) Characterisation of spin coated engineered Escherichia coli biofilms using atomic force microscopy. Colloids and Surfaces B: Biointerfaces 89: 152-160
Tsoligkas, AN, Winn, M, Bowen, J, Overton, TW, Simmons, MJH, and Goss, RJM. (2011) Engineering Biofilms for Biocatalysis. ChemBioChem 12: 1391-1395
Company
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